• Duo-A Nightly 1% Retinoid Treatment 30ml
  • Duo-A Nightly 1% Retinoid Treatment 30ml
  • Duo-A Nightly 1% Retinoid Treatment 30ml
  • Duo-A Nightly 1% Retinoid Treatment 30ml
  • Duo-A Nightly 1% Retinoid Treatment 30ml
  • Duo-A Nightly 1% Retinoid Treatment 30ml
1 6

By Cosmedix

Duo-A Nightly 1% Retinoid Treatment 30ml

Advanced Dual-Retinoid Renewal for Experienced Users
$261.00
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The evolution of Vitamin A skincare. Duo-A is an advanced nightly retinoid treatment exclusively available in Australia and New Zealand, formulated for experienced retinoid users ready to elevate their anti-ageing results. Combining 1% Retinol and fast-acting Retinal (Retinaldehyde) in a single formula, Duo-A targets fine lines, wrinkles, uneven skin tone, and texture for visibly smoother, firmer, and brighter skin overnight.

Fortified with Beta-Glucan to strengthen the skin barrier, Aloe Vera to soothe visible redness, and Vitamin E to nourish and protect - Duo-A delivers professional-grade results while supporting the skin through the renewal process. Ideal for pre-treatment preparation for in-clinic peels and microneedling. Available at Sanctuary Skin Care, Neutral Bay.

Pickup available at Sanctuary Skin Care

Usually ready in 24 hours
Benefits
  • 1% Retinol and Retinal (Retinaldehyde) combined for comprehensive dual-retinoid skin renewal
  • Reduces the visible appearance of fine lines, wrinkles, and uneven skin texture
  • Stimulates collagen production for a firmer, more youthful-looking complexion
  • Improves skin tone and helps fade visible pigmentation and discolouration
  • Beta-Glucan strengthens the skin's barrier and helps prevent moisture loss
  • Aloe Vera soothes and reduces visible redness during retinoid use
  • Vitamin E protects against environmental and oxidative damage
  • Ideal pre-treatment preparation for peels and microneedling
  • Exclusively available in Australia and New Zealand
  • PM use only - always wear SPF daily
Best For
  • Experienced retinoid users ready to step up their Vitamin A routine
  • Visible fine lines, wrinkles, and loss of skin firmness
  • Uneven skin tone, pigmentation, and dull complexion
  • Pre-treatment preparation for peels and microneedling
  • Those wanting professional-grade retinoid results at home
Key Ingredients
  • Retinol (1%) - a clinically proven Vitamin A derivative that stimulates cellular renewal, reduces wrinkles, and improves skin firmness
  • Retinal (Retinaldehyde) - the most potent and fast-acting topical Vitamin A derivative, just one step away from retinoic acid
  • Beta-Glucan - a calming polysaccharide that strengthens the skin's barrier, enhances hydration, and defends against environmental stress
  • Aloe Vera - naturally soothes visible redness and provides gentle hydration during retinoid use
  • Vitamin E (Tocopherol) - antioxidant that nourishes and protects skin from free radical damage
How to Use
  • PM USE ONLY: Apply a pea-sized amount to clean, dry skin at night, avoiding the eye area
  • Begin using 1-3 times per week and gradually increase to nightly as skin builds tolerance
  • Always follow with moisturiser
  • Wear broad-spectrum SPF daily to protect results
  • Discontinue use 48 hours before in-clinic treatments (peels, microneedling)
  • Not suitable for beginners to Vitamin A, those who are pregnant, or those breastfeeding

Frequently Asked Questions

Is Duo-A suitable for beginners to retinol?

Duo-A is formulated for experienced retinoid users, not beginners. If you are new to Vitamin A, start with CosMedix Serum 16 or Serum 24 and build tolerance before transitioning to Duo-A.
How do I introduce Duo-A into my routine?

Begin using Duo-A 1-3 times per week, gradually increasing frequency as your skin adjusts. Apply a pea-sized amount to clean, dry skin at night, avoiding the eye area, then follow with moisturiser. Always wear SPF during the day.
Can Duo-A be used in preparation for in-clinic treatments?

Yes - Duo-A is specifically noted as ideal preparation for in-clinic Today and Tomorrow peels, as well as microneedling. Its dual-retinoid formula helps prime the skin for advanced treatments. Discontinue use 48 hours prior to treatment.